KMT5C

Across TCGA patient cohorts, KMT5C RNA expression is significantly associated with the protein abundance of many other proteins, with 9,930 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KMT5C-associated proteins across cancer lineages are ADNP, RPRD1B, and SAE1. Each is linked with KMT5C in more than 5 cancer types. Because this analysis shows association rather than direction, both KMT5C-to-partner and partner-to-KMT5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMT5C versus ADNP in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT5C→partner) and Y-score (partner→KMT5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADNP →	+0.307	+0.325	<.001	<.001	3	6
GBM	RPRD1B →	+0.431	+0.389	<.001	.001	3	4
GBM	SAE1 →	+0.267	+0.334	<.001	<.001	3	4
COAD	SF3B3 →	+0.228	+0.719	<.001	<.001	3	4
GBM	HNRNPLL →	+0.273	+0.437	<.001	<.001	3	4
LSCC	HSPBP1 →	+0.233	+0.508	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,930 associations by consensus.

KMT5C vs ADNP — GBM

Explore this scatter interactively →