KMT5B

Across TCGA patient cohorts, KMT5B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,504 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KMT5B-associated proteins across cancer lineages are HNRNPLL, NCKAP1L, and NUMA1. Each is linked with KMT5B in more than 5 cancer types. Because this analysis shows association rather than direction, both KMT5B-to-partner and partner-to-KMT5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMT5B versus HNRNPLL in LSCC, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT5B→partner) and Y-score (partner→KMT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HNRNPLL →	+0.276	+0.613	<.001	<.001	3	6
GBM	NCKAP1L →	-0.506	-0.358	<.001	.001	3	6
LSCC	NUMA1 →	+0.500	+0.657	<.001	<.001	3	6
LSCC	GATAD2B →	+0.375	+0.632	<.001	<.001	3	6
GBM	BTK →	-0.417	-0.392	<.001	<.001	3	6
GBM	PLEK →	-0.458	-0.304	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,504 associations by consensus.

KMT5B vs HNRNPLL — LSCC

Explore this scatter interactively →