KMT5B

Across TCGA patient cohorts, KMT5B protein abundance is significantly associated with the RNA expression of many other genes, with 10,626 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KMT5B-associated genes across cancer lineages are LINC02416, ETV2, and PLXDC2. Each is linked with KMT5B in more than 2 cancer types. Because this analysis shows association rather than direction, both KMT5B-to-partner and partner-to-KMT5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMT5B versus LINC02416 in PDAC, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT5B→partner) and Y-score (partner→KMT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	LINC02416 →	-1.100	-0.740	.006	.002	3	3
GBM	ETV2 →	+0.300	+0.407	.002	.001	3	2
GBM	PLXDC2 →	-0.517	-0.373	.008	<.001	3	2
GBM	ANXA11 →	-0.498	-0.438	<.001	<.001	3	2
LUAD	EGLN3 →	+1.594	+0.396	<.001	.002	3	2
GBM	MYOF →	-0.781	-0.437	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,626 associations by consensus.

KMT5B vs LINC02416 — PDAC

Explore this scatter interactively →