KMT5B

Across TCGA cell cohorts, KMT5B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,469 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KMT5B-associated GO terms across cancer lineages are Regulation of stem cell population maintenance, Protein modification by small protein removal, and Positive regulation of DNA recombination. Each is linked with KMT5B in more than 12 cancer types. Because this analysis shows association rather than direction, both KMT5B-to-partner and partner-to-KMT5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of stem cell population maintenance grouped by KMT5B-low versus KMT5B-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT5B→partner) and Y-score (partner→KMT5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of stem cell population maintenance →	+0.082	+0.659	.001	.005	3	13
CNS	Protein modification by small protein removal →	+0.044	+0.414	<.001	.001	3	13
LUNG_SCLC	Positive regulation of DNA recombination →	+0.072	+0.742	.001	.003	3	12
LUNG_SCLC	Regulation of DNA repair →	+0.056	+0.761	<.001	.003	3	12
LUNG_SCLC	Golgi organization →	+0.066	+0.974	<.001	<.001	3	12
LARGE_INTESTINE	Heterochromatin organization →	+0.065	+0.863	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,469 associations by consensus.

Regulation of stem cell population maintenance by KMT5B expression — BREAST

Explore this box plot interactively →