KMT5AP1

Across TCGA patient cohorts, KMT5AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,971 significant associations in total. OV shows the largest number of these associations.

The most reproducible KMT5AP1-associated GO terms across cancer lineages are Regulation of centriole replication, Centrosome duplication, and Centriole assembly. Each is linked with KMT5AP1 in more than 29 cancer types. Because this analysis shows association rather than direction, both KMT5AP1-to-partner and partner-to-KMT5AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole replication grouped by KMT5AP1-low versus KMT5AP1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT5AP1→partner) and Y-score (partner→KMT5AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Regulation of centriole replication →	+0.071	+0.156	<.001	<.001	3	30
DLBC	Centrosome duplication →	+0.061	+0.148	<.001	<.001	3	29
DLBC	Centriole assembly →	+0.062	+0.167	<.001	<.001	3	28
DLBC	Mitotic G2 DNA damage checkpoint signaling →	+0.051	+0.163	<.001	<.001	3	27
THYM	Cytokinesis →	+0.048	+0.130	<.001	<.001	3	27
DLBC	Nuclear-transcribed mRNA catabolic process →	+0.050	+0.200	.003	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,971 associations by consensus.

Regulation of centriole replication by KMT5AP1 expression — DLBC

Explore this box plot interactively →