KMO

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KMO RNA expression is significantly associated with the protein abundance of many other proteins, with 20,184 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KMO-associated proteins across cancer lineages are DOCK2, WIPF1, and RENBP. Each is linked with KMO in more than 8 cancer types. Because this analysis shows association rather than direction, both KMO-to-partner and partner-to-KMO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMO versus DOCK2 in OV, with a Pearson correlation of 0.53.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KMO→partner) and Y-score (partner→KMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDOCK2 →+0.772+0.724<.001<.00139
OVWIPF1 →+0.518+0.525<.001.00439
OVRENBP →+0.506+0.494<.001.00339
GBMLCP1 →+0.855+0.737<.001<.00139
GBMLCP2 →+0.570+0.766<.001<.00139
OVLPXN →+0.809+0.677<.001.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,184 associations by consensus.

KMO vs DOCK2 — OV

Per-sample scatter of KMO vs DOCK2 in OV (Pearson r = 0.53).

Explore this scatter interactively →

Exploration