KMO

Across TCGA patient cohorts, KMO protein abundance is significantly associated with the RNA expression of many other genes, with 17,355 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KMO-associated genes across cancer lineages are DLG3, ACP5, and AQP9. Each is linked with KMO in more than 3 cancer types. Because this analysis shows association rather than direction, both KMO-to-partner and partner-to-KMO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMO versus DLG3 in LUAD, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KMO→partner) and Y-score (partner→KMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DLG3 →	-0.398	-0.271	<.001	<.001	3	4
GBM	ACP5 →	+1.134	+0.795	.003	<.001	3	3
CCRCC	AQP9 →	+1.118	+0.668	.001	<.001	3	3
GBM	JAK3 →	+0.987	+0.723	.005	.006	3	3
LUAD	LPXN →	+0.485	+0.279	<.001	.003	3	3
GBM	MS4A6A →	+0.989	+0.986	.009	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,355 associations by consensus.

KMO vs DLG3 — LUAD

Explore this scatter interactively →