KMO

Across TCGA cell cohorts, KMO RNA expression is significantly associated with the go_rna of many other GO terms, with 4,347 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KMO-associated GO terms across cancer lineages are Positive regulation of eating behavior, Positive regulation of glutamate secretion, neurotransmission, and CD8-positive, alpha-beta T cell activation. Each is linked with KMO in more than 11 cancer types. Because this analysis shows association rather than direction, both KMO-to-partner and partner-to-KMO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of eating behavior grouped by KMO-low versus KMO-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KMO→partner) and Y-score (partner→KMO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of eating behavior →	+1.456	+0.749	<.001	<.001	2	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of glutamate secretion, neurotransmission →	-0.161	-0.593	.001	.001	2	9
SOFT_TISSUE	CD8-positive, alpha-beta T cell activation →	+0.141	+0.355	<.001	<.001	3	8
BLOOD_Leukemia	CD8-positive, alpha-beta T cell differentiation →	+0.067	+0.568	.004	<.001	3	8
LARGE_INTESTINE	Indole-containing compound catabolic process →	-0.274	-0.480	<.001	.002	3	8
LUNG_NSCLC_LUAD	Regulation of glutamate secretion, neurotransmission →	-0.131	-0.628	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,347 associations by consensus.

Positive regulation of eating behavior by KMO expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →