Across TCGA patient cohorts, KLRG2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,908 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLRG2-associated genes across cancer lineages are EEF1AKMT4, FAM83D, and MTPAP. Each is linked with KLRG2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLRG2-to-partner and partner-to-KLRG2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRG2→partner) and Y-score (partner→KLRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EEF1AKMT4 →	+0.886	+0.686	<.001	<.001	3	4
HNSC	FAM83D →	+1.070	+0.961	.004	<.001	3	3
BRCA	MTPAP →	+0.528	+1.113	<.001	<.001	3	3
LSCC	ARHGEF6 →	-0.501	-0.824	.007	.002	3	3
BRCA	PSAT1 →	+1.886	+0.742	<.001	<.001	3	3
LSCC	IL36RN →	+0.960	+0.573	.002	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,908 associations by consensus.

Exploration

KLRG2 survival (RNA) · tumor vs normal (RNA) · all KLRG2 data types