Across TCGA patient cohorts, KLRG2 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLRG2-associated genes across cancer lineages are BANF1P5, MIR1266, and CHCHD2P3. Each is linked with KLRG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRG2-to-partner and partner-to-KLRG2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRG2→partner) and Y-score (partner→KLRG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BANF1P5 →	+0.263	+3.253	.005	.005	3	2
COAD	MIR1266 →	+0.592	+5.790	<.001	.003	3	2
UCEC	CHCHD2P3 →	+0.213	+3.018	.001	.009	3	1
UCEC	H4C7 →	+0.562	+4.398	<.001	<.001	3	1
UCEC	ASCL3 →	+0.409	+3.686	.001	.004	3	1
UCEC	OR2M7 →	+0.193	+3.833	.004	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Exploration

KLRG2 survival (RNA) · tumor vs normal (RNA) · all KLRG2 data types