KLRG1

Across TCGA patient cohorts, KLRG1 protein abundance is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KLRG1-associated genes across cancer lineages are RBMX2P5, MTND4P24, and MMP15. Each is linked with KLRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRG1-to-partner and partner-to-KLRG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLRG1 versus RBMX2P5 in LUAD, with a Pearson correlation of 0.84.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRG1→partner) and Y-score (partner→KLRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RBMX2P5 →	+0.215	+0.798	<.001	<.001	3	1
LUAD	MTND4P24 →	+0.475	+0.798	<.001	<.001	3	1
LUAD	MMP15 →	-1.283	-0.231	.006	<.001	2	1
LUAD	THBS4 →	-2.719	-0.203	.009	.002	2	1
LUAD	ATP8A1 →	-0.820	-0.203	.005	.002	2	1
LUAD	RUSF1 →	-0.491	-0.203	.002	.002	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

KLRG1 vs RBMX2P5 — LUAD

Explore this scatter interactively →