KLRG1

Across TCGA cell cohorts, KLRG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,188 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KLRG1-associated GO terms across cancer lineages are tRNA methylation, Mitochondrial RNA metabolic process, and Mitochondrial DNA replication. Each is linked with KLRG1 in more than 11 cancer types. Because this analysis shows association rather than direction, both KLRG1-to-partner and partner-to-KLRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA methylation grouped by KLRG1-low versus KLRG1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRG1→partner) and Y-score (partner→KLRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	tRNA methylation →	+0.057	+1.176	.003	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitochondrial RNA metabolic process →	+0.098	+0.570	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Mitochondrial DNA replication →	+0.118	+0.559	.001	.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA double-strand break processing →	+0.101	+0.490	<.001	<.001	3	11
BONE	tRNA processing →	+0.063	+1.215	.002	.001	3	11
OVARY	Tetrapyrrole metabolic process →	+0.096	+1.094	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,188 associations by consensus.

tRNA methylation by KLRG1 expression — LUNG_SCLC

Explore this box plot interactively →