KLRG1

Across TCGA cell cohorts, KLRG1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KLRG1-associated genes across cancer lineages are OR51Q1, TENT5D, and OR52E4. Each is linked with KLRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRG1-to-partner and partner-to-KLRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR51Q1 grouped by KLRG1-low versus KLRG1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRG1→partner) and Y-score (partner→KLRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR51Q1 →	+0.099	+3.662	.008	.009	3	1
LUNG_SCLC	TENT5D →	+0.102	+4.000	<.001	.003	3	1
LUNG_SCLC	OR52E4 →	+0.134	+3.925	<.001	.004	3	1
LUNG_SCLC	OR52N1 →	+0.124	+4.256	<.001	.002	3	1
LUNG_SCLC	OR52H1 →	+0.059	+4.256	<.001	.002	3	1
LUNG_SCLC	OR52E8 →	+0.032	+4.058	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR51Q1 by KLRG1 expression — LUNG_SCLC

Explore this box plot interactively →