KLRF2

Across TCGA cell cohorts, KLRF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 115 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLRF2-associated GO terms across cancer lineages are Hydrogen peroxide-mediated programmed cell death, Detection of bacterium, and Cell growth. Each is linked with KLRF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLRF2-to-partner and partner-to-KLRF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hydrogen peroxide-mediated programmed cell death grouped by KLRF2-low versus KLRF2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLRF2→partner) and Y-score (partner→KLRF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Hydrogen peroxide-mediated programmed cell death →	-0.075	-0.403	<.001	.007	3	2
BLOOD_Leukemia	Detection of bacterium →	+0.184	+0.865	.002	.001	3	2
BLOOD_Leukemia	Cell growth →	+0.042	+0.795	<.001	.003	3	2
BLOOD_Leukemia	Regulation of potassium ion import →	+0.174	+1.120	<.001	.002	3	2
BLOOD_Leukemia	Intrinsic apoptotic signaling pathway in response to hydrogen peroxide →	-0.075	-0.403	<.001	.007	3	2
BLOOD_Leukemia	Detection of other organism →	+0.146	+0.718	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

Hydrogen peroxide-mediated programmed cell death by KLRF2 expression — BLOOD_Leukemia

Explore this box plot interactively →