Across TCGA patient cohorts, KLKP1 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLKP1-associated genes across cancer lineages are ASB17, SSTR5, and BCRP6. Each is linked with KLKP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLKP1-to-partner and partner-to-KLKP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLKP1→partner) and Y-score (partner→KLKP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASB17 →	+0.194	+3.355	<.001	.004	3	1
UCEC	SSTR5 →	+0.888	+3.506	<.001	.007	3	1
UCEC	BCRP6 →	+0.092	+3.492	.001	.003	3	1
UCEC	TBC1D3L →	+0.687	+3.626	.001	.008	3	1
UCEC	IGHV4-4 →	+2.010	+3.690	<.001	.007	3	1
UCEC	IL26 →	+0.230	+3.630	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

KLKP1 survival (RNA) · tumor vs normal (RNA) · all KLKP1 data types