Across TCGA patient cohorts, KLK9 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,708 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible KLK9-associated GO terms across cancer lineages are Keratinocyte differentiation, Epidermal cell differentiation, and Regulation of epidermis development. Each is linked with KLK9 in more than 11 cancer types. Because this analysis shows association rather than direction, both KLK9-to-partner and partner-to-KLK9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK9→partner) and Y-score (partner→KLK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Keratinocyte differentiation →	+0.086	+0.676	<.001	<.001	3	12
SKCM	Epidermal cell differentiation →	+0.069	+0.164	<.001	<.001	3	11
ESCA	Regulation of epidermis development →	+0.066	+0.673	<.001	<.001	3	11
STAD	Regulation of keratinocyte differentiation →	+0.068	+0.040	<.001	<.001	3	10
STAD	Positive regulation of epidermis development →	+0.058	+0.059	<.001	<.001	3	10
BRCA	Regulation of protein localization to lysosome →	+0.062	+0.028	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,708 associations by consensus.

Exploration

KLK9 survival (RNA) · tumor vs normal (RNA) · all KLK9 data types