Across TCGA cell cohorts, KLK9 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KLK9-associated genes across cancer lineages are ACOD1, CABP5, and CFC1. Each is linked with KLK9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLK9-to-partner and partner-to-KLK9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK9→partner) and Y-score (partner→KLK9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ACOD1 →	+0.006	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	CABP5 →	+0.012	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	CFC1 →	+0.879	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	MMP26 →	+0.056	+5.643	.001	.002	3	1
BLOOD_Lymphoma	OR11H6 →	+0.018	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

KLK9 survival (RNA) · tumor vs normal (RNA) · all KLK9 data types