KLK2

Across TCGA cell cohorts, KLK2 RNA expression is significantly associated with the RNA expression of many other genes, with 2,775 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLK2-associated genes across cancer lineages are MAGEA3, KLK3, and KLK4. Each is linked with KLK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLK2-to-partner and partner-to-KLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK2 versus MAGEA3 in SKIN, with a Pearson correlation of 0.44.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK2→partner) and Y-score (partner→KLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	MAGEA3 →	+2.732	+0.680	<.001	<.001	3	4
LARGE_INTESTINE	KLK3 →	+0.973	+0.296	<.001	<.001	3	4
LARGE_INTESTINE	KLK4 →	+1.055	+0.280	<.001	<.001	3	4
SKIN	CSAG1 →	+2.801	+0.831	<.001	<.001	3	3
SKIN	MAGEA2B →	+2.778	+0.799	<.001	.001	3	3
SOFT_TISSUE	POTEI →	+0.233	+0.128	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,775 associations by consensus.

KLK2 vs MAGEA3 — SKIN

Explore this scatter interactively →