KLK12

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KLK12 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,027 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KLK12-associated GO terms across cancer lineages are Regulation of phosphate transport, Cellular response to indole-3-methanol, and Negative regulation of inflammatory response to wounding. Each is linked with KLK12 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLK12-to-partner and partner-to-KLK12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK12→partner) and Y-score (partner→KLK12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of phosphate transport →+0.581+2.253.002<.00134
LUNG_SCLCCellular response to indole-3-methanol →+0.152+2.758<.001<.00134
LUNG_SCLCNegative regulation of inflammatory response to wounding →+0.204+3.260<.001<.00133
LUNG_SCLCHexose phosphate transport →+0.482+3.665.001<.00133
LUNG_SCLCGlucose-6-phosphate transport →+0.482+3.665.001<.00133
LUNG_SCLCActivation of GTPase activity →+0.108+2.294.001.00633
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,027 associations by consensus.

Exploration