KLK11

Across TCGA patient cohorts, KLK11 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,356 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLK11-associated proteins across cancer lineages are KLK10, SERPINB5, and TNKS1BP1. Each is linked with KLK11 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLK11-to-partner and partner-to-KLK11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK11 versus KLK10 in BRCA, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK11→partner) and Y-score (partner→KLK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KLK10 →	+1.384	+3.194	<.001	<.001	3	7
COAD	SERPINB5 →	+1.511	+1.541	<.001	<.001	3	5
HNSC	TNKS1BP1 →	+0.322	+1.241	<.001	<.001	3	5
HNSC	ICAM1 →	-0.453	-1.372	<.001	<.001	3	4
LSCC	IL1RN →	+0.761	+1.351	<.001	<.001	3	4
LSCC	VSNL1 →	+1.114	+1.436	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,356 associations by consensus.

KLK11 vs KLK10 — BRCA

Explore this scatter interactively →