KLK11

Across TCGA cell cohorts, KLK11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,146 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible KLK11-associated GO terms across cancer lineages are Antimicrobial peptide production, Antimicrobial peptide biosynthetic process, and Antibacterial peptide production. Each is linked with KLK11 in more than 8 cancer types. Because this analysis shows association rather than direction, both KLK11-to-partner and partner-to-KLK11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Antimicrobial peptide production grouped by KLK11-low versus KLK11-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK11→partner) and Y-score (partner→KLK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Antimicrobial peptide production →	+1.275	+2.028	<.001	<.001	3	9
OVARY	Antimicrobial peptide biosynthetic process →	+1.275	+2.028	<.001	<.001	3	9
OVARY	Antibacterial peptide production →	+1.275	+2.028	<.001	<.001	3	9
OVARY	Antibacterial peptide biosynthetic process →	+1.275	+2.028	<.001	<.001	3	9
LARGE_INTESTINE	Negative regulation of hippocampal neuron apoptotic process →	+1.231	+1.914	<.001	.003	3	8
LUNG_SCLC	Sensory perception of salty taste →	+1.199	+2.454	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,146 associations by consensus.

Antimicrobial peptide production by KLK11 expression — OVARY

Explore this box plot interactively →