KLK10

Across TCGA patient cohorts, KLK10 protein abundance is significantly associated with the RNA expression of many other genes, with 7,629 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLK10-associated genes across cancer lineages are KLK11, KLK13, and KLK12. Each is linked with KLK10 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLK10-to-partner and partner-to-KLK10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLK10 versus KLK11 in BRCA, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK10→partner) and Y-score (partner→KLK10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KLK11 →	+3.194	+1.384	<.001	<.001	3	7
LUAD	KLK13 →	+1.904	+1.140	<.001	<.001	3	7
LUAD	KLK12 →	+3.191	+0.979	<.001	<.001	3	7
HNSC	KLK8 →	+1.527	+1.094	<.001	<.001	3	4
HNSC	SULT2B1 →	+1.607	+1.249	<.001	<.001	3	4
HNSC	KLK14 →	+2.527	+1.076	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,629 associations by consensus.

KLK10 vs KLK11 — BRCA

Explore this scatter interactively →