KLHL7

Across TCGA cell cohorts, KLHL7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,577 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHL7-associated GO terms across cancer lineages are Meiotic mismatch repair, Positive regulation of isotype switching to IgG isotypes, and Endocytic recycling. Each is linked with KLHL7 in more than 13 cancer types. Because this analysis shows association rather than direction, both KLHL7-to-partner and partner-to-KLHL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Meiotic mismatch repair grouped by KLHL7-low versus KLHL7-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL7→partner) and Y-score (partner→KLHL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Meiotic mismatch repair →	+0.127	+0.779	<.001	<.001	3	14
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.134	+1.013	.001	<.001	3	12
KIDNEY	Endocytic recycling →	+0.049	+0.642	<.001	<.001	3	12
BLOOD_Myeloma	Negative regulation of chromosome segregation →	+0.118	+1.176	<.001	<.001	3	11
LARGE_INTESTINE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.066	+0.756	<.001	<.001	3	11
OESOPHAGUS	Intracellular transport of virus →	+0.136	+0.690	.004	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,577 associations by consensus.

Meiotic mismatch repair by KLHL7 expression — STOMACH

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