KLHL36

Across TCGA patient cohorts, KLHL36 protein abundance is significantly associated with the RNA expression of many other genes, with 7,126 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible KLHL36-associated genes across cancer lineages are SYNPO2, KPNA2, and GTSE1. Each is linked with KLHL36 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLHL36-to-partner and partner-to-KLHL36 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL36 versus SYNPO2 in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL36→partner) and Y-score (partner→KLHL36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SYNPO2 →	+1.250	+0.255	<.001	<.001	3	4
LUAD	KPNA2 →	-0.739	-0.209	<.001	<.001	3	4
GBM	GTSE1 →	-0.974	-0.252	<.001	<.001	3	4
LUAD	CALCOCO2 →	+0.546	+0.290	<.001	<.001	3	4
LUAD	MIR29B2CHG →	+0.850	+0.295	<.001	<.001	3	4
UCEC	GIMAP1 →	+0.495	+0.201	.003	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,126 associations by consensus.

KLHL36 vs SYNPO2 — UCEC

Explore this scatter interactively →