KLHL36

Across TCGA cell cohorts, KLHL36 mutation is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KLHL36-associated genes across cancer lineages are OR10G4, OR4M2, and MSGN1. Each is linked with KLHL36 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL36-to-partner and partner-to-KLHL36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10G4 grouped by KLHL36-low versus KLHL36-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL36→partner) and Y-score (partner→KLHL36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR10G4 →	+0.020	+3.515	<.001	.003	3	2
LUNG_NSCLC_LUAD	OR4M2 →	+0.267	+4.887	<.001	.009	3	2
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	2
LARGE_INTESTINE	C14orf180 →	+0.177	+4.155	<.001	.003	3	2
SOFT_TISSUE	C1orf87 →	+0.169	+4.291	.003	<.001	3	1
SOFT_TISSUE	KCNC2 →	+0.795	+3.263	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

OR10G4 by KLHL36 expression — SOFT_TISSUE

Explore this box plot interactively →