KLHL35

Across TCGA cell cohorts, KLHL35 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,026 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KLHL35-associated GO terms across cancer lineages are Protein localization to endoplasmic reticulum, Regulation of myoblast fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with KLHL35 in more than 8 cancer types. Because this analysis shows association rather than direction, both KLHL35-to-partner and partner-to-KLHL35 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to endoplasmic reticulum grouped by KLHL35-low versus KLHL35-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL35→partner) and Y-score (partner→KLHL35) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein localization to endoplasmic reticulum →	+0.111	+1.569	.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.085	+1.017	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.079	+1.041	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Biogenic amine biosynthetic process →	-0.107	-1.278	.001	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.045	+1.061	.005	.001	3	7
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.128	+1.150	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,026 associations by consensus.

Protein localization to endoplasmic reticulum by KLHL35 expression — OESOPHAGUS

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