Across TCGA patient cohorts, KLHL33 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,167 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL33-associated proteins across cancer lineages are PPP1R12B, PRKG1, and ILK. Each is linked with KLHL33 in more than 8 cancer types. Because this analysis shows association rather than direction, both KLHL33-to-partner and partner-to-KLHL33 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL33→partner) and Y-score (partner→KLHL33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PPP1R12B →	+0.890	+0.324	<.001	.003	3	8
UCEC	PRKG1 →	+1.045	+0.493	<.001	.001	3	8
UCEC	ILK →	+0.980	+0.710	<.001	<.001	3	8
UCEC	KANK2 →	+0.759	+0.436	<.001	<.001	3	8
BRCA	KANK2_S375 →	+0.611	+0.291	<.001	<.001	3	8
UCEC	CNRIP1 →	+1.330	+0.664	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,167 associations by consensus.

Exploration

KLHL33 survival (RNA) · tumor vs normal (RNA) · all KLHL33 data types