KLHL29

Across TCGA cell cohorts, KLHL29 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,789 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KLHL29-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Regulation of hematopoietic stem cell differentiation, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with KLHL29 in more than 10 cancer types. Because this analysis shows association rather than direction, both KLHL29-to-partner and partner-to-KLHL29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by KLHL29-low versus KLHL29-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL29→partner) and Y-score (partner→KLHL29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.101	+1.093	.002	.001	3	11
BONE	Regulation of hematopoietic stem cell differentiation →	+0.110	+1.380	<.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.095	+1.093	.003	.001	3	10
SOFT_TISSUE	Negative regulation of translation →	+0.060	+1.986	<.001	<.001	3	9
BONE	DNA-templated transcription termination →	+0.076	+1.068	.001	.001	3	9
SOFT_TISSUE	Transcription by RNA polymerase I →	+0.099	+1.770	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,789 associations by consensus.

Negative regulation of myoblast fusion by KLHL29 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →