KLHL26

Across TCGA patient cohorts, KLHL26 protein abundance is significantly associated with the RNA expression of many other genes, with 5,347 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KLHL26-associated genes across cancer lineages are PITPNC1, SPRY1, and PLEKHA8P1. Each is linked with KLHL26 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHL26-to-partner and partner-to-KLHL26 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL26 versus PITPNC1 in OV, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL26→partner) and Y-score (partner→KLHL26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PITPNC1 →	+1.275	+0.518	.001	.007	3	3
BRCA	SPRY1 →	+0.972	+0.327	<.001	<.001	3	3
LSCC	PLEKHA8P1 →	-0.427	-0.177	.003	.002	3	3
GBM	EMX2OS →	+0.884	+0.270	<.001	.001	3	3
OV	CAPN9 →	+1.604	+0.418	.004	.006	3	2
OV	CA3 →	-1.201	-0.505	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,347 associations by consensus.

KLHL26 vs PITPNC1 — OV

Explore this scatter interactively →