KLHL20

Across TCGA cell cohorts, KLHL20 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,566 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHL20-associated GO terms across cancer lineages are Golgi vesicle transport, Endosomal transport, and Cytosolic transport. Each is linked with KLHL20 in more than 15 cancer types. Because this analysis shows association rather than direction, both KLHL20-to-partner and partner-to-KLHL20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by KLHL20-low versus KLHL20-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL20→partner) and Y-score (partner→KLHL20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Golgi vesicle transport →	+0.073	+0.574	<.001	.001	3	16
BONE	Endosomal transport →	+0.064	+0.576	.009	.001	2	15
BONE	Cytosolic transport →	+0.077	+0.617	.001	.001	2	15
BONE	Retrograde transport, endosome to Golgi →	+0.074	+0.437	.002	.008	3	14
OESOPHAGUS	Post-Golgi vesicle-mediated transport →	+0.083	+0.580	.001	.009	3	14
SKIN	Regulation of translational initiation →	+0.058	+0.785	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,566 associations by consensus.

Golgi vesicle transport by KLHL20 expression — BONE

Explore this box plot interactively →