Across TCGA patient cohorts, KLHL17 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,334 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLHL17-associated proteins across cancer lineages are UHRF1, DHX15, and TAF12. Each is linked with KLHL17 in more than 4 cancer types. Because this analysis shows association rather than direction, both KLHL17-to-partner and partner-to-KLHL17 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL17→partner) and Y-score (partner→KLHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UHRF1 →	+0.495	+0.597	.001	.003	3	5
GBM	DHX15 →	+0.190	+0.504	.005	<.001	3	5
GBM	TAF12 →	+0.355	+0.557	<.001	<.001	3	5
GBM	RBM17 →	+0.194	+0.375	<.001	<.001	3	4
BRCA	RCC1 →	+0.313	+0.720	<.001	.002	3	4
LSCC	RCC2 →	+0.367	+0.436	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,334 associations by consensus.

Exploration

KLHL17 survival (RNA) · tumor vs normal (RNA) · all KLHL17 data types