Across TCGA patient cohorts, KLHL17 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,330 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KLHL17-associated proteins across cancer lineages are ATG2B_S497, BAG4_S179, and ACTB. Each is linked with KLHL17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL17-to-partner and partner-to-KLHL17 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL17→partner) and Y-score (partner→KLHL17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ATG2B_S497 →	+1.299	+0.430	<.001	.005	3	1
PDAC	BAG4_S179 →	+2.018	+0.631	<.001	.001	3	1
PDAC	ACTB →	+0.649	+0.514	<.001	<.001	3	1
PDAC	ACTG1 →	+1.316	+0.514	.001	<.001	3	1
PDAC	BCL6_S457 →	-0.617	-0.730	<.001	.001	3	1
PDAC	ACTR1B →	+0.475	+0.514	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,330 associations by consensus.

Exploration

KLHL17 survival (RNA) · tumor vs normal (RNA) · all KLHL17 data types