KLHL15

Across TCGA patient cohorts, KLHL15 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,031 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL15-associated proteins across cancer lineages are RBBP7, WRNIP1, and HUWE1. Each is linked with KLHL15 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLHL15-to-partner and partner-to-KLHL15 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL15 versus RBBP7 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL15→partner) and Y-score (partner→KLHL15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RBBP7 →	+0.510	+0.625	.003	<.001	3	6
GBM	WRNIP1 →	+0.298	+0.298	.007	.004	3	5
GBM	HUWE1 →	+0.277	+0.340	<.001	<.001	3	5
LSCC	PARP1 →	+0.404	+0.528	.001	.004	3	5
HNSC	STRBP →	+0.578	+0.752	<.001	<.001	3	5
LSCC	RPRD2 →	+0.254	+0.571	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,031 associations by consensus.

KLHL15 vs RBBP7 — OV

Explore this scatter interactively →