KLHL10

Across TCGA patient cohorts, KLHL10 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,508 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLHL10-associated proteins across cancer lineages are STIM1_S257, SEC63_T537, and AKAP13_S2498. Each is linked with KLHL10 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLHL10-to-partner and partner-to-KLHL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL10 versus STIM1_S257 in PDAC, with a Pearson correlation of -0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL10→partner) and Y-score (partner→KLHL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	STIM1_S257 →	-0.820	-0.173	<.001	<.001	3	6
PDAC	SEC63_T537 →	-0.845	-0.183	<.001	<.001	3	5
CCRCC	AKAP13_S2498 →	-0.694	-0.167	<.001	<.001	3	5
PDAC	GATAD2B_S334 →	+0.440	+0.173	<.001	<.001	2	6
PDAC	LZTS1_S233 →	+1.055	+0.182	<.001	<.001	3	5
CCRCC	ZNF704_S77 →	+0.698	+0.232	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,508 associations by consensus.

KLHL10 vs STIM1_S257 — PDAC

Explore this scatter interactively →