KLHL10

Across TCGA patient cohorts, KLHL10 mutation is significantly associated with the RNA expression of many other genes, with 3,751 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHL10-associated genes across cancer lineages are BNIP3P41, RNU6-1317P, and LINC01810. Each is linked with KLHL10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL10-to-partner and partner-to-KLHL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by KLHL10-low versus KLHL10-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL10→partner) and Y-score (partner→KLHL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	BNIP3P41 →	+0.036	+5.412	<.001	.001	3	2
HNSC	RNU6-1317P →	+2.093	+7.954	<.001	.008	3	2
HNSC	LINC01810 →	+0.089	+7.954	<.001	.008	3	2
BLCA	RNA5SP457 →	+0.501	+4.758	<.001	.003	3	2
BLCA	RNU5A-6P →	+0.370	+4.533	.003	.005	3	2
STAD	MIR4765 →	+0.523	+5.051	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,751 associations by consensus.

BNIP3P41 by KLHL10 expression — COAD

Explore this box plot interactively →