KLHL10

Across TCGA cell cohorts, KLHL10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,321 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible KLHL10-associated GO terms across cancer lineages are Positive regulation of potassium ion transmembrane transport, Positive regulation of sodium ion transport, and Cardiac muscle cell action potential. Each is linked with KLHL10 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLHL10-to-partner and partner-to-KLHL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of potassium ion transmembrane transport grouped by KLHL10-low versus KLHL10-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL10→partner) and Y-score (partner→KLHL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of potassium ion transmembrane transport →	-0.144	-0.070	.002	.003	3	7
OVARY	Positive regulation of sodium ion transport →	-0.216	-0.094	<.001	.002	3	6
STOMACH	Cardiac muscle cell action potential →	-0.141	-0.065	.004	.005	3	6
LARGE_INTESTINE	Inorganic cation import across plasma membrane →	-0.069	-0.048	<.001	.001	2	7
LARGE_INTESTINE	Inorganic ion import across plasma membrane →	-0.069	-0.048	<.001	.001	2	7
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle G2/M phase transition →	+0.070	+0.120	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,321 associations by consensus.

Positive regulation of potassium ion transmembrane transport by KLHL10 expression — OVARY

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