KLHDC9

Across TCGA patient cohorts, KLHDC9 mutation is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHDC9-associated genes across cancer lineages are SNORD116-3, MRPL35P4, and RAB28P2. Each is linked with KLHDC9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHDC9-to-partner and partner-to-KLHDC9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-3 grouped by KLHDC9-low versus KLHDC9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC9→partner) and Y-score (partner→KLHDC9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNORD116-3 →	+0.564	+4.299	<.001	<.001	3	2
UCEC	MRPL35P4 →	+0.303	+5.345	<.001	<.001	3	2
UCEC	RAB28P2 →	+0.104	+4.137	<.001	.008	3	2
COAD	RNU6-822P →	+0.591	+5.435	<.001	.005	3	2
COAD	PUDPP1 →	+0.167	+5.357	<.001	.006	3	2
COAD	MIR6842 →	+0.788	+5.693	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

SNORD116-3 by KLHDC9 expression — UCEC

Explore this box plot interactively →