Across TCGA patient cohorts, KLHDC8B protein abundance is significantly associated with the RNA expression of many other genes, with 2,564 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KLHDC8B-associated genes across cancer lineages are PIP4P2, EIF2B1, and MCM8. Each is linked with KLHDC8B in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHDC8B-to-partner and partner-to-KLHDC8B results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC8B→partner) and Y-score (partner→KLHDC8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PIP4P2 →	+0.889	+0.470	.001	.003	3	3
LUAD	EIF2B1 →	-0.350	-0.288	.004	.006	3	2
LUAD	MCM8 →	-0.596	-0.262	.001	.009	3	2
LSCC	CHTF18 →	-0.517	-0.348	<.001	<.001	3	2
LSCC	TACC3 →	-0.582	-0.291	<.001	.006	3	2
GBM	PPP2R3B →	-0.643	-0.317	.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,564 associations by consensus.

Exploration

KLHDC8B survival (RNA) · tumor vs normal (RNA) · all KLHDC8B data types