Across TCGA patient cohorts, KLHDC8B mutation is significantly associated with the RNA expression of many other genes, with 1,996 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHDC8B-associated genes across cancer lineages are MIR4762, IGHD3-16, and BNIP3P41. Each is linked with KLHDC8B in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHDC8B-to-partner and partner-to-KLHDC8B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC8B→partner) and Y-score (partner→KLHDC8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4762 →	+0.356	+4.867	<.001	.005	3	2
UCEC	IGHD3-16 →	+1.780	+3.358	<.001	<.001	3	2
UCEC	BNIP3P41 →	+0.014	+4.571	<.001	.002	3	2
SKCM	MIR596 →	+0.486	+4.993	<.001	.002	3	2
UCEC	PPIAP75 →	-0.291	-2.652	.003	.006	3	1
UCEC	RPL23AP90 →	+0.330	+2.293	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,996 associations by consensus.

Exploration

KLHDC8B survival (RNA) · tumor vs normal (RNA) · all KLHDC8B data types