Across TCGA cell cohorts, KLHDC8B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,801 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHDC8B-associated GO terms across cancer lineages are Protoporphyrinogen IX biosynthetic process, Vesicle cargo loading, and Nucleoside triphosphate metabolic process. Each is linked with KLHDC8B in more than 10 cancer types. Because this analysis shows association rather than direction, both KLHDC8B-to-partner and partner-to-KLHDC8B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC8B→partner) and Y-score (partner→KLHDC8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protoporphyrinogen IX biosynthetic process →	+0.137	+1.706	<.001	<.001	3	10
OESOPHAGUS	Vesicle cargo loading →	+0.088	+2.115	.001	<.001	2	11
OVARY	Nucleoside triphosphate metabolic process →	+0.066	+1.059	<.001	<.001	3	9
OVARY	Purine ribonucleoside triphosphate metabolic process →	+0.079	+1.192	<.001	<.001	3	9
STOMACH	Protoporphyrinogen IX metabolic process →	+0.120	+2.573	.009	<.001	2	10
BREAST	Cell division →	+0.065	+1.258	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,801 associations by consensus.

Exploration

KLHDC8B survival (RNA) · tumor vs normal (RNA) · all KLHDC8B data types