Across TCGA cell cohorts, KLHDC8B mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible KLHDC8B-associated genes across cancer lineages are OR10W1, BPIFA1, and RAX. Each is linked with KLHDC8B in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHDC8B-to-partner and partner-to-KLHDC8B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC8B→partner) and Y-score (partner→KLHDC8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.012	+3.240	<.001	.004	3	1
LARGE_INTESTINE	BPIFA1 →	+0.145	+2.688	<.001	.008	3	1
OVARY	RAX →	+0.272	+3.662	<.001	.009	3	1
OVARY	GPR101 →	+0.012	+3.990	.003	.003	3	1
OVARY	OR52I2 →	+0.021	+4.263	<.001	.002	3	1
OVARY	TBX5 →	+0.280	+4.095	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

KLHDC8B survival (RNA) · tumor vs normal (RNA) · all KLHDC8B data types