KLHDC8A

Across TCGA patient cohorts, KLHDC8A RNA expression is significantly associated with the protein abundance of many other proteins, with 12,092 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLHDC8A-associated proteins across cancer lineages are HDGFL3, DEF6, and TYMP. Each is linked with KLHDC8A in more than 5 cancer types. Because this analysis shows association rather than direction, both KLHDC8A-to-partner and partner-to-KLHDC8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHDC8A versus HDGFL3 in COAD, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC8A→partner) and Y-score (partner→KLHDC8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	HDGFL3 →	+0.623	+0.245	<.001	.001	3	5
OV	DEF6 →	-0.370	-1.477	<.001	<.001	3	5
GBM	TYMP →	-0.855	-1.298	<.001	<.001	3	5
COAD	MAP1B →	+0.646	+0.298	<.001	<.001	3	5
LSCC	MAP1B_S1427 →	+1.255	+0.551	<.001	.008	3	5
LUAD	MAP1B_S1779 →	+1.247	+0.709	<.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,092 associations by consensus.

KLHDC8A vs HDGFL3 — COAD

Explore this scatter interactively →