KLHDC8A

Across TCGA patient cohorts, KLHDC8A protein abundance is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLHDC8A-associated genes across cancer lineages are CYP1A2, CYB5D1, and LINC00700. Each is linked with KLHDC8A in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHDC8A-to-partner and partner-to-KLHDC8A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHDC8A versus CYP1A2 in GBM, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC8A→partner) and Y-score (partner→KLHDC8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYP1A2 →	+0.046	+0.523	.006	.001	2	1
GBM	CYB5D1 →	+0.096	+0.523	.002	.001	2	1
GBM	LINC00700 →	+0.023	+0.523	.002	.001	2	1
GBM	MLIP-IT1 →	+0.486	+0.524	<.001	.003	2	1
GBM	RPL35AP11 →	+0.476	+0.523	<.001	.001	2	1
GBM	LINC02517 →	+0.056	+0.523	.001	.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

KLHDC8A vs CYP1A2 — GBM

Explore this scatter interactively →