KLHDC7B-DT

Across TCGA pan-cancer cohorts, KLHDC7B-DT RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated KLHDC7B-DT data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KLHDC7B-DT RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KLHDC7B-DT expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUAD show a favorable association.

KIRC, UVM, and SKCM are the cancer types where KLHDC7B-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.531	0.729	<.001	156	view →
UVM	OS	Tertile	All	0.357	0.789	<.001	105	view →
SKCM	OS	Median	All	0.451	0.255	<.001	86	view →
PAAD	OS	Median	All	0.379	0.590	<.001	67	view →
KIRP	DFS	Quartile	II,III,IV	0.315	0.853	.003	61	view →
LUAD	DFS	Quartile	III,IV	0.652	0.310	<.001	55	view →
LGG	DFS	Median	All	0.659	0.810	<.001	43	view →
KICH	OS	Median	III,IV	0.468	1.000	.001	36	view →
THYM	DFS	Quartile	All	0.499	0.910	.001	25	view →
GBM	OS	Quartile	All	0.259	0.640	.002	24	view →
THCA	DFS	Quartile	II,III,IV	0.551	0.905	.002	23	view →
CESC	DFS	Quartile	All	0.858	0.683	.013	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

KLHDC7B-DT–KIRC (OS)

Open the KIRC breakdown →