KLHDC4

Across TCGA patient cohorts, KLHDC4 protein abundance is significantly associated with the RNA expression of many other genes, with 6,808 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KLHDC4-associated genes across cancer lineages are REL, DGKH, and TMEM30A. Each is linked with KLHDC4 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLHDC4-to-partner and partner-to-KLHDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHDC4 versus REL in OV, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC4→partner) and Y-score (partner→KLHDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	REL →	-0.613	-0.516	.006	.004	3	4
COAD	DGKH →	-0.689	-0.496	.003	.001	3	4
OV	TMEM30A →	-0.620	-0.592	.001	.004	3	3
OV	TRAK2 →	-0.588	-0.613	.007	.009	3	3
OV	SLC13A4 →	-0.643	-0.570	.009	.007	3	3
OV	PXK →	-0.656	-0.577	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,808 associations by consensus.

KLHDC4 vs REL — OV

Explore this scatter interactively →