KLHDC4

Across TCGA patient cohorts, KLHDC4 mutation is significantly associated with the RNA expression of many other genes, with 3,438 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHDC4-associated genes across cancer lineages are RN7SL237P, RNU6-653P, and SNORD114-10. Each is linked with KLHDC4 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHDC4-to-partner and partner-to-KLHDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL237P grouped by KLHDC4-low versus KLHDC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC4→partner) and Y-score (partner→KLHDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL237P →	+0.206	+1.707	<.001	.002	3	3
COAD	RNU6-653P →	+0.876	+4.516	<.001	.001	3	2
COAD	SNORD114-10 →	+0.695	+4.251	<.001	.008	3	2
COAD	RN7SKP44 →	+0.216	+4.435	<.001	.001	3	2
COAD	SNORD114-6 →	+0.916	+4.917	<.001	.003	3	2
COAD	SNORD32B →	+0.387	+5.409	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

RN7SL237P by KLHDC4 expression — UCEC

Explore this box plot interactively →