KLHDC4

Across TCGA cell cohorts, KLHDC4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,781 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHDC4-associated GO terms across cancer lineages are Late viral transcription, RNA catabolic process, and RNA surveillance. Each is linked with KLHDC4 in more than 14 cancer types. Because this analysis shows association rather than direction, both KLHDC4-to-partner and partner-to-KLHDC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Late viral transcription grouped by KLHDC4-low versus KLHDC4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC4→partner) and Y-score (partner→KLHDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Late viral transcription →	+0.136	+1.083	<.001	<.001	3	15
BONE	RNA catabolic process →	+0.078	+1.170	.001	.001	3	15
BLOOD_Lymphoma	RNA surveillance →	+0.065	+1.019	<.001	<.001	3	15
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.142	+1.057	<.001	<.001	3	15
BONE	Nucleic acid transport →	+0.143	+1.364	<.001	<.001	3	15
BONE	RNA transport →	+0.143	+1.364	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,781 associations by consensus.

Late viral transcription by KLHDC4 expression — BONE

Explore this box plot interactively →