KLHDC1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KLHDC1 mutation is significantly associated with the RNA expression of many other genes, with 871 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLHDC1-associated genes across cancer lineages are RNA5SP534, MIR615, and RNA5SP300. Each is linked with KLHDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLHDC1-to-partner and partner-to-KLHDC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHDC1→partner) and Y-score (partner→KLHDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRNA5SP534 →+0.674+6.624<.001.00133
UCECMIR615 →+0.260+2.232<.001.00732
UCECRNA5SP300 →+0.152+3.038<.001.00632
UCECKRTAP4-16 →+0.061+2.513.002.00732
UCECRNU7-22P →+0.123+3.973.004.00632
SKCMDMRTC1 →+0.029+6.469<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 871 associations by consensus.

Exploration