KLF9

Across TCGA pan-cancer cohorts, KLF9 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KLF9 data layer compared with 20 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher KLF9 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated KLF9 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

LUAD, GBM, and LSCC are the cancer types where KLF9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.178	1.000	.024	6	view →
GBM	OS	Quartile	All	0.884	0.332	.024	3	view →
LSCC	OS	Median	II,III,IV	0.997	0.660	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KLF9–LUAD (DFS)

Open the LUAD breakdown →