KLF6

Across TCGA patient cohorts, KLF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,006 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLF6-associated proteins across cancer lineages are TRIM47_S588, ZYX, and ZYX_S344. Each is linked with KLF6 in more than 6 cancer types. Because this analysis shows association rather than direction, both KLF6-to-partner and partner-to-KLF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF6 versus TRIM47_S588 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF6→partner) and Y-score (partner→KLF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM47_S588 →	+0.406	+0.540	<.001	<.001	3	7
OV	ZYX →	+0.401	+0.968	.002	.008	3	6
OV	ZYX_S344 →	+0.900	+1.080	.002	.001	3	6
LSCC	SNX9 →	+0.317	+0.618	<.001	<.001	3	6
COAD	KLKB1 →	+0.528	+0.689	.004	<.001	3	6
BRCA	APOC3 →	+0.763	+0.840	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,006 associations by consensus.

KLF6 vs TRIM47_S588 — LSCC

Explore this scatter interactively →